AKT1 and osteosarcoma: In veterinary oncology, AKT expression have been reported in FMTs [22] in canine hemangiosarcoma [17,34], osteosarcoma [18], melanoma [35,36], neuroepithelial [37], and perianal [38] tumors, squamous cell carcinoma [39,40], and mast cell tumors [41].