Snail-induced FSTL1 directly damages CTL induction [35], and indirectly through the induction of pluripotent mesenchymal stem/stromal cells (MSCs), which not only generate dysfunctional CD8low CTLs via ALCAM signaling but also further promote tumor metastasis, especially to the bone marrow [31]. Here, FSTL1 is linked to neoplasm.