Table 5 also displays that the immune cells such as total T cells, total B cells, MHC II (major histocompatibility complex type II), CD4+ T cells, CD8+ T cells, NK cells, and macrophages in the P. cocos extract group had no significant difference compared with the control group. Based on the above results, it should be assessed that there should be no risk of immunotoxicity during the P. cocos extract feeding experiment. Here, CD4 is linked to immune system toxicity.