The renal transplantation of a kidney from a Drd5 knockout mouse, which is hypertensive, to a nephrectomized wild-type mouse, which is normotensive, promotes hypertension while the renal transplantation of a kidney from a wild-type mouse to a nephrectomized Drd5 knockout mouse, which is hypertensive, normalizes blood pressure [148]. This evidence concerns the gene DRD5 and Hypertension.