Indeed, a strong correlation has been found between the prevalence and severity of anemia, the prevalence of increased mean plasma levels of inflammation markers-including C-reactive protein (CRP), fibrinogen, interleukin (IL)-6, tumor necrosis factor (TNF)-α, IL-1β, erythrocyte sedimentation rate, ferritin, hepcidin, erythropoietin, and reactive oxygen species—and the stage of cancer [3,6,7]. Here, HAMP is linked to anemia (phenotype).