MeV vectors encoding ovalbumin (OVA) as model antigen or the tumor antigen claudin-6 either in native form or in association with lentivirus-like particles were shown to induce antigen-specific humoral and cellular immune responses in IFN-α receptor (IFNAR)-deficient, CD46-transgenic mice and prolong survival in B16-derived tumor models [114]. Here, IFNAR1 is linked to neoplasm.