NLRP3 and CINCA syndrome: Dominant missense mutations in the NLRP3 gene in humans result in a hyperactive NLRP3 inflammasome and overproduction of inflammatory cytokines, leading to CAPS, a group of autoinflammatory diseases that include familial cold autoinflammatory syndrome (FCAS), Muckle–Wells syndrome (MWS), and neonatal onset multisystem inflammatory disease (NOMID) [25,26].