To assess whether changes in lung adipokine mRNA levels seen in human IPAH are recapitulated in experimental PH, we evaluated mRNA levels of FABP-4, FGF-21, and PPARγ in rat lungs and found them significantly upregulated in all three models of experimental PH (Figure 3). The gene discussed is FABP4; the disease is idiopathic pulmonary arterial hypertension.