Focusing back on alterations of androgens in autistic disorder epitestosterone might yield to hyperserotonemia influencing tryptophan metabolism [23,24,25], impairment of neurotransmitter systems [26,27,28,29,30], slower cortisol response during ACTH stimulation [31,32], higher ACTH levels [33], higher fetal testosterone [4], high DHEA [34], increased plasma oxalate levels [35], reduced pyridoxal kinase activity [27], which all might relate back to androgen dysregulation potentially influenced by epitestosterone in individuals with autism. Here, PDXK is linked to autism.