As previously shown [7, 32], Th2 cells are crucial in fibrotic disorders by shifting the cytokine balance towards Th2 dominance; this finding was consistent with our results that inhibiting Th2 cell recruitment using the anti-VAP-1 antibody alleviated the progression of hepatic capillarization or even liver fibrosis by altering the Th2 dominance. Here, AOC3 is linked to Hepatic fibrosis.