The main biological processes of genes in green-yellow module contained were immune response, adaptive immune response, B cell receptor (BCR) signaling pathway, and primary immunodeficiency; Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis found that the main enriched signaling pathways were BCR signaling pathway, cytokine-cytokine receptor interaction, and NF-κB activity. The gene discussed is BCR; the disease is inborn error of immunity.