When used properly, real-time continuous glucose monitors in conjunction with multiple daily injections and continuous subcutaneous insulin infusion [A], and other forms of insulin therapy [C] are a useful tool to lower and/or maintain A1C levels and/or reduce hypoglycemia in adults and youth with diabetes.Use of professional CGM and/or intermittent real-time or intermittently scanned CGM can be helpful in identifying and correcting patterns of hyperglycemia and hypoglycemia, and improving A1C levels in people with diabetes on noninsulin, as well as basal insulin regimens. [C]. This evidence concerns the gene INS and Hyperglycemia.