IL1B and neoplasm: In contrast, in lung cancer (Wang et al. 2016), prostate cancer (Chen et al. 2013), breast cancer (Weichand et al. 2017), and head and neck squamous cell carcinoma (Bae et al. 2017), the NLRP3 inflammasome, IL-1β, and IL-18 promote tumor growth, proliferation, invasion, and metastasis.