The mechanism of EndMT and the upregulated lncRNA Gm16410 was further investigated and it was found that lncRNA Gm16410 mediates PM2.5‐induced EndMT by regulating the TGF‐β1/Smad3/p‐Smad3 pathway, which highlights the potential of lncRNAs to promote pulmonary fibrosis under environmental pollution.57 This evidence concerns the gene TGFB1 and pulmonary fibrosis.