Transgenic pancreatic cancer mouse models (Ptf1a+/Cre; Kras+/LSL‐G12D; Trp53loxP/loxP, and Ptf1a+/Cre; Kras+/LSL‐G12D; Trp53loxP/loxP; Egfr/f1/f1). Here, PTF1A is linked to familial pancreatic carcinoma.