Compared to those with prevalent dementia (n = 266, Figure 1), individuals with incident dementia (n = 605) had a higher age at death (P < .001) and a lower frequency of APOE ɛ4 carriers (P = .049), while no differences were found in sex, the AD‐PRSs (the 39‐SNPs AD‐PRS and 1e–5 AD‐PRS), or age at baseline. The gene discussed is APOE; the disease is Alzheimer disease.