BIRC5 and psoriasis: In our study, we found that the level of VEGF was increased, and YXJD inhibited the excessive expression of VEGF as well as the secretion of VEGF and related proteins expression in HUVEC cells transfected by Survivin overexpression and IMQ-induced psoriasis-like mouse model, which inferred YXJD can ameliorate the abnormal neovascularization in psoriasis (Figure 9).