Thus, identification of various associated risk factors of AD such as type 2 diabetes, hyperhomocysteinemia, hypercholesterolemia, hypovitaminosis D, altered levels of pro-inflammatory cytokines, adiponectin and leptin etc. in the early phase of the disease and application of suitable corrective measures through life-style management and drugs may prove more beneficial instead of searching for a ‘magic bullet’ to cure AD. This evidence concerns the gene ADIPOQ and Alzheimer disease.