Therefore, in order to prove whether Fbxo21 is involved in the regulation of these processes of gastric cancer, we used SGC-7901, BGC-823, MGC-803 and MKN28 cells that were transduced with the Fbxo21-siRNA vector, the Fbxo21 expression vector or the negative control vector, and assessed cell migration and invasion using the transwell migration assay, the wound healing assay and the Matrigel-coated transwell assay, respectively (Figure 2). Here, FBXO21 is linked to gastric cancer.