FBXO21 and gastric cancer: We also examined Fbxo21 protein level in seven cell lines: GES1, MKN45, SGC-7901, BGC-823, MGC-803, AGS and MKN28 cells, and found a similar trend to the results in tissue: Fbxo21 protein expression was lower in six gastric cancer cell lines (Figure 1D), compared with GES1.