The results revealed that the mRNA expression of IGFBP7 was significantly increased in the G3 phase (P<0.001, Figure 3C), advanced tumor status (T2/3/4) (P<0.001, Figure 3D) and advanced stages (II/III/IV) (P<0.05, Figure 3G). This evidence concerns the gene IGFBP7 and neoplasm.