The pathological changes of HFD-induced NAFLD were also more serious in the GPRC6ALKO : HFD + OCN group than that of the WT : HFD + OCN group (Figure 3(b), 3(d), 3(f), 3(h), and 3(i)), which suggested that uncarboxylated osteocalcin did not protect GPRC6ALKO mice from HFD-induced hepatic steatosis. Here, BGLAP is linked to metabolic dysfunction-associated steatotic liver disease.