The overlapping candidate genes for (b) IR and AF breeds include, Echinoderm microtubule-associated protein-like 5 (EML5) on chromosome seven, may change the assembly dynamics of microtubules to make microtubules are slightly longer but more dynamic and it is possible that EML5 plays a role during neuronal development in the regulation of cytoskeletal rearrangements, IQ domain-containing protein E (IQCE) on chromosome 24, involved in body development, TRNA-YW Synthesizing Protein 1 Homolog B (TYW1B) on chromosome 24, influenced on the wybutosine biosynthesis pathway. This evidence concerns the gene EML5 and atrial fibrillation.