Among the four clusters of dendritic cells, DC_C2_CD1C, DC_C3_LAMP3, and DC_C4_JCHAIN were derived from tumours, and DC_C1_FCER1A was derived from peripheral blood, which was assigned as monocyte-like DC because of the expression of monocyte marker S100A8 (Supplementary Fig. 8a, b). The gene discussed is S100A8; the disease is neoplasm.