PDCD1 and nasopharyngeal carcinoma: Consistently, in another independent NPC sample collection (n = 113), we observed strong correlations of expression among the gene signatures for DC_C3_LAMP3 cells, Treg cells, and exhausted CD8+ T cells (CD8_C11_PDCD1; r > 0.8, P < 2.2 × 10−16; Supplementary Fig. 11b).