Noteworthily, we identified DC_C3_LAMP3 cells as a group of DCs with high maturation, activation, and migration potentials in NPC, based on the expression levels of the signature genes related to maturation (LAMP3, MARCKSL1, IDO1, and UBD), activation (CD80, CD83, and CD40), and migration (CCR7, FSCN1, and SLCO5A1; Fig. 4b, Supplementary Fig. 8c and Supplementary Table 5), respectively. The gene discussed is CD80; the disease is nasopharyngeal carcinoma.