In the subgroup analysis of different diagnostic groups, those associations between methylation levels of BIN1 promoter and Aβ-related biomarkers still remained significant in SCD subgroup (Aβ42, p = 0.0006; p-tau/Aβ42, p < 0.0001; t-tau/Aβ42, p < 0.0001) but not in CN subgroup. The gene discussed is MAPT; the disease is Schnyder corneal dystrophy.