METTL3 and carcinoma: In hepatocellular carcinoma, METTL3-mediated m6A modification results in the upregulation of LINC00958 by stabilizing its mRNA, and LINC00958 sponges miR-3619-5p to upregulate hepatocellular carcinoma-derived growth factor (HDGF) expression to facilitate hepatocellular carcinoma progression and lipogenesis19.