NPPB and diabetes mellitus: This study aimed to perform a head-to-head comparison of the predictive performance of the ESC/EASD model against SCORE and NT-proBNP for risk assessment of 10-year CVD death and all-cause death (i) in an unselected type 2 diabetes mellitus (T2DM) cohort, (ii) in selected patients with T2DM with characteristics similar to the SCORE derivation cohort and (iii) to investigate the outcome-specific performance of the different risk estimates.