Jørgesen et al. have previously shown that N-terminal pro b-type natriuretic peptide (NT- proBNP) in combination with changes in electrocardiography predicted all-cause mortality and cardiovascular events in patients without previous cardiac disease [8], but the predictive value of natriuretic peptides on the incidence of IHD has not been adequately studied. Here, NPPB is linked to myocardial ischemia.