In addition, granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage colony-stimulating factor (GM-CSF) secreted from cancer cells act via signal transducer and activator of transcription (STAT)3/5 in a paracrine manner on MDSCs, resulting in overexpression of CD36 and enhancement in uptake of FAs. Here, CSF2 is linked to cancer.