MAPK1 and nasopharyngeal carcinoma: Nasopharyngeal carcinoma-derived exosomes were shown to be enriched in miRNAs that target and inhibit the MAPK1 and JAK/STAT pathways in T cells, impairing their function and proliferation and inducing the differentiation of Tregs, being associated with the upregulation of exosomal miRNAs, which down-regulate the MAPK1 and JAK/STAT pathways [132].