The gene polymorphisms of adiponectin rs266729 [154], adiponectin-encoding gene (ADIPOQ), leptin receptor (LEPR), apolipoprotein C3 (APOC3), peroxisome proliferator-activated receptors (PPAR), sterol regulatory element-binding proteins (SREBP), transmembrane 6 superfamily member 2 (TM6SF2), microsomal triglyceride transfer protein (MTTP), tumor necrosis factor-alpha (TNF-α), and manganese superoxide dismutase (MnSOD) have been reported to be related to NAFLD and coronary artery disease [155]. This evidence concerns the gene LEPR and metabolic dysfunction-associated steatotic liver disease.