Liver-specific knockout of mitochondrial long-chain fatty acid transport protein (carnitine palmitoyltransferase 2, CPT2) [96], inhibition of the mitochondrial ATP transporter (adenine nucleotide translocase 2, ANT2) [97], and deletion of the mitochondrial flavoprotein apoptosis-inducing factor (AIF) [98] have each been shown to ameliorate NAFLD. The gene discussed is CPT2; the disease is metabolic dysfunction-associated steatotic liver disease.