Figure 2 shows that PTENz7-87 biotin aptamer detects PTEN protein in normal endometrium (Figure 2A) and hyperplasic tissue (Figure 2E) but not in adenocarcinoma tissue. Specificity was further confirmed by blocking with PTEN peptide (Figure 2C) and recombinant GST-PTEN protein (Figure 2D). Additionally, MAb 6H2 mouse monoclonal antibody produced a similar staining compared to PTENz7-87 biotin aptamer (Figure 2B). This evidence concerns the gene PTEN and adenocarcinoma.