SREBF1 and metabolic dysfunction-associated steatotic liver disease: For example, Fenglong point can reduce the expression of SREBP-1c in NAFLD rats, improve endoplasmic reticulum stress, and regulate abnormal lipid metabolism.[14] In addition, Vitamin E plays an important role in improving alanine aminotransferase (ALT), aspartate aminotransferase (AST), NAFLD activity score (NAS), liver fibrosis degree.[15,16] Moreover, studies have shown that exercise training reduces intrahepatic fat and FFAs while increasing cardiorespiratory fitness.[17]