TGF‐β signaling is a recognized central mediator of renal fibrosis, possibly through its ability to inhibit miR‐29s capacity to suppress the deposition of collagen Types I, III, and IV by mesangial cells, tubular cells and podocytes in both humans and rodent models.155, 173, 174, 175. This evidence concerns the gene TGFB1 and renal fibrosis.