In the single-covariate models, we observed that anemia was more frequent in nonwhite patients and patients with fewer years of study, history of past alcohol use, drug use, low BMI, lower Karnofsky score, history of weight loss, previous TB treatment, hospitalizations, HIV infection (more frequent in those with CD4<200 cells/μL and interrupted ART), disseminated or meningeal clinical forms, positive smear diagnosis, higher platelet count, microcytosis or hypochromia. The gene discussed is CD4; the disease is anemia.