NRP1 and meningioma: Future targeted therapies of high-grade meningioma may include NRP-1-specific treatment, as experimentally shown by Tirand et al. (Tirand et al. 2006), who could photosensitize endothelial cells with a NRP-1 specific protein bound to the photosensitizer leading to a 25-fold increased uptake of the agent into endothelial cells.