TBP and leukemia: It is also possible that leukemic gene expression by MYB involves additional transcriptional co-activators, such as TAF12, as part of the recently described TFIID-SAGA complex interaction (Xu et al., 2018), or other TAFs which have also been implicated in transcriptional co-regulation in leukemias (Jian et al., 2017; Xu et al., 2019).