EP300 and hematopoietic and lymphoid cell neoplasm: For example, this may involve transcription factor acetylation by CBP/P300 (Roe et al., 2015; Wang et al., 2011), warranting the investigation of recently developed selective CBP/P300 acetyltransferase inhibitors, which have shown particular activity in hematopoietic cancers (Lasko et al., 2017).