Beyond TBI, the self-propagation and prion-like spread of Tau aggregates is thought to play a key role in the progression of other tauopathies such as AD (Iba et al., 2013; Iba et al., 2015; Mudher et al., 2017; Narasimhan et al., 2017; Sanders et al., 2014). This evidence concerns the gene MAPT and Alzheimer disease.