In line with this finding, blocking the cancer‐induced up‐regulation of FoxO1 via AAV2/9 delivery of FoxO1‐shRNA prevented the C26‐induced increase in FoxP1 mRNA (Figure1H)—thus demonstrating the sufficiency and requirement of FoxO1 for FoxP1 up‐regulation. The gene discussed is FOXP1; the disease is cancer.