PCSK9 and diabetes mellitus: Another study in 568,448 subjects (average plasma LDL‐C of 3.41 mmol/L) reported an increase of 0.09 mmol/L in fasting plasma glucose and 29% in the diabetes risk for every 1 mmol/L decrease in plasma LDL‐C attributed to 4 PCSK9 LOF variants (Schmidt et al., 2016).