In several glioma cell lines [58, 59] and in a multiple myeloma cell line [60], the reduction of MET expression by shRNA-mediated knockdown [58, 60] or antisense oligodeoxynucleotides [59] enhanced the effect of temozolamide [58], paclitaxel [59] or doxorubicin [60], in reducing cell survival. The gene discussed is MET; the disease is AL amyloidosis.