They reported that stroke patients with the STin 12/10 polymorphism (lower 5-HTT expression) tended to attain better functional recovery in response to an SSRI than did those with STin 12/12 polymorphism (higher 5-HTT expression)19 and stroke patients with the low 5-HTT expression genotype showed poorer cognitive recovery in response to the placebo compared to the SSRI20. This evidence concerns the gene SLC6A4 and stroke disorder.