Indeed, we identified over 850 sQTLs co-localizing with known asthma loci, affecting the splicing patterns of genes related to immunity, including interleukins and immune cell receptors (IL13, TLSP, IL1RL1, TLR1), major histocompatibility complex components (HLA-DQA1, HLA-DQB1) or interferon-activated transcription factors (IRF1). Here, IRF1 is linked to asthma.