An Akt/FoxM1/STMN1 pathway was found as a mechanism for tyrosine kinase inhibitors (TKIs) resistance in non-small cell lung cancer (NSCLC).15 Since a growing body of evidence has demonstrated the importance of FoxM1 as a hub gene in the oncogenic network, it is emergent to further identify the novel downstream targets regulated by FoxM1. This evidence concerns the gene STMN1 and non-small cell lung carcinoma.