CCNB1 and colorectal carcinoma: Our previous study also showed that silencing of FoxM1 in human LIHC cells results in cell cycle arrest and inhibits cell survival depending on downregulated CCNB1 in G2/M.4 In our present study, our luciferase report assay, ChIP-qPCR and ChIP-seq data analysis in public database demonstrate the mechanism that STMN1 is a direct target of FoxM1 in LIHC, GC and CRC (Fig. 2c–e).