Inhibition of STMN1 results in reduction of cellular proliferation and accumulation of cells in G2/M.11 In the human fibroblasts, deletion of STMN1 induces genomic instability during mitosis and consequently leads to senescence.24 In tumor cells, STMN1 is a tumor promoter contributing to cell proliferation,25 invasion, migration26,27 and drug resistance.14,28 Several studies showed that inhibition of STMN1 can promote the sensitivity of anti-mitotic agents such as taxanes (i.e., docetaxel) and vinca alkaloids (i.e., vinblastine, vincristine). Here, STMN1 is linked to neoplasm.