Additionally, IL-13 receptor alpha 2 has been found to inhibit the detrimental tissue remodeling induced by IL-13 in murine models of both lung inflammation and eosinophilic esophagitis, a chronic inflammation of the esophagus (Zheng et al. 2008; Zuo et al. 2010). This evidence concerns the gene IL13 and eosinophilic esophagitis.