In a cohort of patients with MM treated with HDM and ASCT, polymorphisms in DNA repair genes, including poly(ADP-ribose) polymerase1 (PARP1), RAD51, PCNA, OGG1, XPC, BRCA1, ERCC1, BARD1, and TP53BP1, were associated with the outcome and overall survival [44]. This evidence concerns the gene PARP1 and Miyoshi myopathy.