MVK and mevalonic aciduria: In MKD, as a consequence of the enzymatic deficiency of MVK in the mevalonate pathway, the low availability or lack of the isoprenoid moieties (farnseylpyrophosphate and geranylgeranylpyrophosphate) compromises the correct localization and functions of prenylated proteins, thus affecting, among the other biological functions, erythropoiesis and causing anemia.