Among all the differentially expressed genes in the retinal organoids and monolayer cultures, 10 genes (BDKRB1, BDKRB2, CXCL1, MMP9, F3, RARRES2, PTGS2, IL33, LY96, and VCAM1) were upregulated after the infection by the SARS-CoV-2 pseudovirus. The gene discussed is MMP9; the disease is infection.