VEGFA and age-related macular degeneration: In a cellular model of AMD (ARPE-19 cells), it was also demonstrated that the use of RSV-loaded poly(lactic-co-glyolic acid) (PLGA) nanoparticles (optimized formulation with a particle size of 102.7 nm) improved RSV cellular uptake and increased RSV-induced inhibition of VEGF expression [172].