A further epigenomic analysis involving the generation of 268 epigenomic datasets found that reprogrammed AR chromatin binding sites in PCa are usually occupied by FOXA1 and HOXB13 in the normal prostate, thus pointing to specific metastatic and lineage reprogramming roles for HOXB13, FOXA1, and NKX3-1 [54]. Here, FOXA1 is linked to posterior cortical atrophy.